Multidisciplinary Science Journal <p><strong>Multidisciplinary Science Journal</strong> is the newest multidisciplinary journal of <a href="" target="_blank" rel="noopener"><strong>Malque Publishing</strong></a> in CONTINUOUS FLOW mode. In this new journal, Research Articles, Short Communications, Technical Notes, Case Reports, and Clinical Cases from ALL areas of knowledge are published. Articles are published under the <a href="" target="_blank" rel="noopener">Creative Commons license</a>. </p> <p><strong>High Visibility:</strong> Dimensions, CiteFactor, Scilit, Google Scholar, Diadorim, Directory of Research Journals Indexing, CrossRef, Research Bible, among others. We are already being evaluated for Web of Science (Clarivate Analytics), and CAB International.</p> <p><strong>Rapid Publication:</strong> manuscripts are peer-reviewed. A first decision is provided to authors approximately 25-30 days after submission.</p> <p><strong>Open Access</strong> free for readers, with a low Article Processing Charge (APC) paid by authors or their institutions.</p> <p><strong>New!</strong> In 2022, Article Processing Charge (APC) WILL NOT BE CHARGED for <strong><em>articles submitted in English</em>.</strong></p> en-US (Maiko Dantas) (MSJ Team) Mon, 29 Nov 2021 00:00:00 +0000 OJS 60 Human perceptions and practices related to the squirrel monkeys (<em>Saimiri sciureus</em>) in a forest area of Pernambuco, Brazil <p>In the 1980s, squirrel monkeys (<em>Saimiri sciureus</em>) apprehended during an operation to combat animal trafficking in the state of Pernambuco, Northeastern Brazil, were released into the Atlantic Forest of the Reserva Biológica de Saltinho (REBio Saltinho). As this is an exotic species, which is rapidly disseminated throughout the area, it is necessary to understand the perceptions and attitudes of the reserve residents, workers, and visitors in order to identify potential interactions, conflicts and social factors that may influence the relationship between people and monkeys. Thus, between April and October 2019, three human groups answered semi-structured questionnaires about their perceptions of the squirrel monkey and their attitudes towards primates. Altogether, 70 people were interviewed, of which 94.3% claimed to know of the squirrel monkey. While residents of the surrounding areas of REBio Saltinho described the squirrel monkey using mainly morphological and behavioral characteristics (65%), workers and visitors related their descriptions to the fact that these animals are invasive in 46% and 40% of responses, respectively. Most respondents (80%) were not bothered by the presence of these monkeys, and 86% denied interacting with the animal, while the remaining 14% admitted to trying to interact with the monkeys in some way, usually through offering food. This research will contribute to the improvement and promotion of the actions of environmental management by REBio Saltinho.</p> Dimas Maranhão de Lima, Juliana Ribeiro de Albuquerque, Maria Adélia Borstelmann de Oliveira Copyright (c) 2021 Multidisciplinary Science Journal Mon, 27 Dec 2021 00:00:00 +0000 Avaliação do perfil epidemiológico de idosos com fraturas transtrocantéricas atendidos em hospital de média complexidade <p>O processo de envelhecimento da população brasileira tem culminado em uma necessidade de reconhecer a existência de uma epidemia ortopédica. Este fenômeno consiste em um aumento no número de fraturas em idosos, em especial as transtrocantéricas. O estudo objetivou avaliar o perfil epidemiológico de pacientes idosos submetidos à osteossíntese de fraturas transtrocantéricas em hospital de média complexidade, visto que esta condição eleva os custos governamentais com internações, cirurgias e reabilitações, representando um grande problema social e econômico, fazendo-se necessário melhor investigação desse fenômeno. Trata-se de um estudo transversal e descritivo com dados de prontuários de idosos acometidos por estas fraturas entre 2016 e 2018. A análise foi realizada no programa R versão 3.4.3. Participaram do estudo 236 pacientes, com média de idade de 82 ± 8,31 anos, com predomínio mulheres, viúvos e hipertensos. A média de duração do internamento foi de 3 ± 8.31 dias, com custo médio de R$ 1.812,00. As fraturas mais encontradas foram 31A2.3 (classificação AO) e III variante (classificação Tronzo). A transfusão sanguínea pré-operatória foi necessária em 43,64% dos casos. Conclui-se que o perfil dos pacientes idosos atendidos neste estudo devido à fratura transtrocantérica apresenta o padrão já reconhecido de vitimização maior de mulheres, sem companheiro e com comorbidades que comprometem o equilíbrio, tais como a hipertensão.</p> José André Melo Barreto Guimarães, Jéssika Cristina de Lima, Gabriel Soares de Souza, Natália Ferreira Barreto Guimarães, Pedro Ferreira Barreto Guimarães, Marcos Cesar Feitosa de Paula Machado, Pauliana Valéria Machado Galvão Copyright (c) 2021 Multidisciplinary Science Journal Fri, 24 Dec 2021 00:00:00 +0000 Contribution of online education in access to higher education in Mozambique: Case of ISCED (2015-2018) <p>The Mozambican Government adopted Distance Education in order to offer study opportunities to populations living far from large urban centres and who could not reach traditional face-to-face teaching. The aim of this article is to demonstrate the contribution of online education, adopted by Higher Institute of Education and Science during a period in which the lack of access to higher education promoted an upsurge of national inequality and the development of distance education was focused on a blended perspective. The research was designed with Mixed method, using the case study method, based on three sources (observation, interviews and documents). We used SPSS 21 (IBM) Amonk, New York, USA and Excel (Microsoft) Washington DC, USA for statistical analysis. In terms of results, it can be seen that the online modality, allows many Mozambicans to have access to higher education in Mozambique through the Virtual Learning Environment</p> Messias Luís Cipriano Uarreno Copyright (c) 2021 Multidisciplinary Science Journal Thu, 13 Jan 2022 00:00:00 +0000 Effect of smoking on the microbiological quality of horse mackerel (<em>Trachurus trachurus</em>) processed and marketed by artisanal fishermen from Vilankulos, Mozambique <p>Smoking is one of the fish conservation techniques used by some artisanal fishing communities. Horse mackerel is a fish widely traded and consumed in Mozambique. This study aimed to evaluate the effect of smoking on the microbiological quality of horse mackerel sold in district Desse in Vilankulos. Twelve samples were collected and analyzed for following microbiological parameters (total viable microorganisms, total coliforms, thermotolerant coliforms, <em>Escherichia coli</em>, <em>Salmonella spp.</em>, <em>Staphylococcos</em> <em>aureus, </em><em>Vibrio cholerae</em> and <em>Vibrio parahaemolyticus</em>). The total viable microorganisms were quantified by the NMKL method and the total coliforms, fecal coliforms, and <em>Escherichia coli</em> were quantified by the MPN method. Statistical analysis were performed using the SPSS program, and data were submitted to the normality test using the Shapiro-Wilk test at a significance level of 5%. The results showed the existence of significant differences in the amount of aerobic microorganisms between frozen horse mackerel (3.59 ± 0.87 CFU/g) and smoked horse mackerel (2.39 ± 0.88 CFU/g), total coliforms (0.22 ± 0.53 CFU/g), and (0.06 ± 0.19 CFU/g), respectively, and thermotolerant coliforms (0.12 ± 0.25 CFU/g) and (0.06 ± 0.19 CFU/g), respectively. Smoked horse mackerel had less contamination compared to the frozen fish. There was no significant growth of other microorganisms analyzed.</p> Maria Aventina Macia Matusse, Venancio Merique Nhavoto Copyright (c) 2021 Multidisciplinary Science Journal Tue, 14 Dec 2021 00:00:00 +0000 Ultrasonographic biometry of the ovaries and follicles in cyclic and non-cyclic Kundhi buffaloe <p>Ultrasonographic and morpho-biometry of the ovaries and follicles of cyclic and non-cyclic Kundhi buffaloes was studied. The buffalos were measured for their left and right ovaries using ultrasonographic and morpho-biometry of the ovaries. The age of non-cyclic buffaloes was 10 ± 2.0 years, and cyclic buffaloes was 8.33 ± 1.87 years; body weight of non-cyclic Kundhi Buffaloes was 377.14 ± 52.19 kg and cyclic buffaloes was 380.77 ± 89.69 kg; the body condition score of non-cyclic buffaloes was 3.78 ± 0.395 and cyclic buffaloes was 4.25 ± 0.43. Statistically, the differences for age and body condition score were significant (P&lt;0.05) and non-significant (P&gt;0.05) for body weight. The ultrasonographical biometry in the length of the left and right ovaries in Kundhi buffalo was 28.68 ± 4.80 and 31.44 ± 6.29 mm, 12.62 ± 2.20 and 12.61±2.51 mm in width, 5.81 ± 1.11 and 5.94 ± 1.66 mm in thickness, 64.28 ± 10.40 and 71.73 ± 11.33 mm in circumference, and 2.61 ± 0.76 and 3.08 ± 0.75 cm<sup>2</sup> in volume, respectively. The differences in the length of the left and right ovaries, circumference, and volume were significant (P&lt;0.05) and non-significant (P&gt;0.05) for width and thickness. The morpho-biometry results indicated that the length of the left and right ovaries was 28.88 ± 5.30 and 30.31 ± 6.61 mm, 14.00 ± 1.83 and 14.00 ± 2.10 mm in width, 6.94 ± 1.12 and 7.06 ± 1.65 mm in thickness, 65.00 ± 7.75 and 68.44 ± 9.44 mm in circumference, and 5.88 ± 2.00 and 5.44 ± 1.63 gm in weight, respectively. The differences in the length, circumference, and weight of left and right ovaries were significant (P&lt;0.05) and non-significant (P&gt;0.05) for width and thickness of ovaries. The number of primary follicles on left and right ovaries was 1.00 ± 0.97 and 1.31 ± 1.08, secondary was 3.31 ± 2.85 and 3.63 ± 3.01, tertiary was 6.38 ± 1.59 and 6.81 ± 2.34, circumference of follicle on the left and right ovaries was 17.58 ± 5.52 and 16.69 ± 4.20 mm, and volume of the follicle 0.24 ± 0.14 and 0.21 ± 0.10 cm<sup>2</sup>. The differences in primary follicles, circumference of the follicle on the right and left ovaries were significant (P&lt;0.05) and non-significant (P&gt;0.05) for secondary, tertiary, and volume of follicles on left and right ovaries. <strong> </strong>The length ovaries in cyclic and non-cyclic Kundhi buffalo was 30.22 ± 6.85 and 29.89 ± 4.43 mm, ovaries 12.65 ± 1.68 and 12.57 ± 2.57 mm in width, 6.58 ± 1.61 and 5.58 ± 1.11 mm in thickness, 70.63 ± 13.06 and 65.38 ± 8.97 mm in circumference, 2.96 ± 0.79 and 2.72 ± 0.76 cm<sup>2</sup> in volume, 6.00 ± 2.06 and 5.31 ± 1.49 gm in weight, respectively. The number of primary follicles on ovaries of cyclic and non-cyclic Kundhi buffaloes was 2.31 ± 1.08 and 0, number of secondary was 5.25 ± 1.77 and 0, number of tertiary was 7.31 ± 1.69 and 3.06 ± 1.30, 17.88 ± 4.93 and 12.30 ± 3.46 mm in circumference, and 0.25 ± 0.13 and 0.10 ± 0.08 cm<sup>2</sup> in volume, respectively. The differences in thickness, circumference (O), weight, number of primary, secondary, tertiary, circumference (F). and volume (F) of follicles of cyclic and non-cyclic Kundhi buffaloes were significant (P&lt;0.05) and non-significant (P&gt;0.05) for length and width of follicles of cyclic and non-cyclic buffaloes.</p> Tahir Iqbal, Adnan Yousaf, Naila BiBi, Lookesh Kumar, Saif-ul-Rehman, Sambreena Tunio, Muhammad Mubashir Farooq, Abdullah Channo, Abdul Wakeel, Zainab Lanjar, Muhammad Ibrahim Panhwar, Ali Gul Soomro, Mathan Copyright (c) 2021 Multidisciplinary Science Journal Thu, 09 Dec 2021 00:00:00 +0000 Cumprimento das metas de periodontia nos Centros de Especialidades Odontológicas do município de São Paulo, SP <p>Este estudo propôs-se em avaliar o cumprimento de metas de produtividade mensais na especialidade de periodontia nos Centros de Especialidades Odontológicas (CEOs) existentes no município de São Paulo, SP, entre 2008 e 2016. O levantamento utilizou dados da produção de procedimentos odontológicos registrados pelo Sistema de Informação Ambulatorial do Sistema Único de Saúde (SIA/SUS). Foram avaliadas as metas de produtividade mensais para a periodontia para os CEOs tipo I (60 procedimentos/mês), tipo II (90 procedimentos/mês) e tipo III (150 procedimentos/mês). Os procedimentos avaliados foram: raspagem coronorradicular, enxerto gengival, gengivectomia, gengivoplastia e tratamento cirúrgico periodontal. Foram avaliados os dados de produtividade de nove CEOs, sendo um do tipo I, seis do tipo II e dois do tipo III. O CEO I ultrapassou a meta em todos os anos avaliados, com os CEOs II e II não atingindo a meta pontualmente. Os procedimentos clínicos foram os mais realizados nos CEOs. Porém, o baixo número de procedimentos cirúrgicos e enxertos gengivais contribuíram para que CEOs tipos II e III não alcançassem as metas de produtividade no período entre 2008 e 2016. A meta estabelecida para os CEOs avaliados foi cumprida pelo CEO I, majoritariamente pelos CEOs II e parcialmente pelos CEOs III. A avaliação dos CEOs otimiza a relação entre a oferta e a taxa de utilização dos serviços a fim de se melhorar a qualidade e a distribuição da atenção secundária.</p> Ana Paula Conrado Dulz, André Luiz Veiga Conrado, Luciana Saraiva Copyright (c) 2021 Multidisciplinary Science Journal Thu, 02 Dec 2021 00:00:00 +0000 Interação molecular entre o reparo tecidual via sinalização SDF-1/CXCR4 e a resposta inflamatória no infarto agudo do miocárdio com supradesnivelamento do segmento-ST <p>A relação resposta inflamatória/dano isquêmico é pré-requisito para início do processo de adaptação do tecido cardíaco pós-infarto, contexto no qual a sinalização SDF-1/CXCR4 desempenha papel central no reparo tecidual. Este estudo objetivou investigar a modulação exercida pelo eixo SDF-1/CXCR4 sobre a resposta inflamatória após infarto agudo do miocárdio com elevação do segmento-ST (STEMI). Para tanto, desenvolvemos Redes Bayesianas a partir de dados de microarranjo (GEO) e avaliamos a expressão dos transcritos de interesse em pacientes com STEMI por qPCR. No contexto pró-inflamatório e agudo pós-infarto observamos forte relação entre proteínas de adesão endotelial e do infiltrado celular. No cenário crônico e anti-inflamatório, verificamos relação entre proteínas envolvidas com remodelamento tecidual e bloqueio de vias apoptóticas. Os níveis de expressão dos transcritos avaliados encontravam-se aumentados nos momentos iniciais pós-infarto. Conclui-se que os efeitos promovidos pela interação SDF-1/CXCR4 podem ser modulados segundo o perfil imunológico, influenciando diretamente nos seus efeitos adaptativos e cardioprotetores.</p> Melissa Kristochek da Silva, Marco Antônio de Bastiani, Lucinara Dadda Dias, Raphael Boesche Guimarães, Marcela Corso Arend, Melissa Medeiros Markoski Copyright (c) 2021 Multidisciplinary Science Journal Mon, 29 Nov 2021 00:00:00 +0000 HER2/p53 ratios among canine mammary tumours and respective derived cell culture <p>In this study, the expression of p53 and human epidermal growth factor receptor 2 (HER2) proteins were investigated in different canine mammary tumors (CMT) and cell cultures derived from them, for the purpose of determining neoplastic behavior <em>in vitro</em>. For this purpose, immunohistochemistry and immunocytochemistry were performed and results were compared according to histological diagnose. CMT were collected and divided into two halves, one for histological and immunohistochemistry analyses and another for cell cultures. Cell markers p53 and HER2 proteins were detected by immunohistochemistry in the original tumors and immunocytochemistry in CMT-derived cell lines. A total of CMT (n = 17) were classified and divided into benign mixed tumor (BMT), complex carcinoma (CC), simple carcinoma (SC), and squamous cell carcinoma (SCC). Low expression of p53 was verified in BMT and CC, averagely in SC and undetectable in SCC. <em>In vitro</em>, there was an increase in p53 expression by cultured cells. However, HER2 protein expression was not significant in BMT, CC and SCC. In contrast, MCT-derived cells were considered HER2-positive in all MCT types. In conclusion, the <em>in vitro</em> model is essential for the study of neoplastic behavior and understanding of the carcinogenic mechanisms that occur <em>in vivo.</em></p> Letícia Colin Panegossi, Tereza Cristina Cardoso Copyright (c) 2021 Multidisciplinary Science Journal Mon, 29 Nov 2021 00:00:00 +0000 Redução de fratura em arco zigomático por acesso intraoral <p>O arco zigomático configura um dos pilares horizontais maxilofaciais e fraturas nessa região são relativamente frequentes dentre as lesões decorrentes de traumas faciais. Podem causar uma série de sequelas, principalmente a limitação mecanica na abertura bucal, e por isso, há indicação de redução cirurgica quando o deslocamento dos fragmentos ósseos interfere na função oral ou estética. As reduções podem ser cruentas seguidas de osteossíntese com placas e parafusos, ou mesmo, através de procedimentos incruentos, menos invasivos e sem necessidade de osteossíntese. Entretanto, o princípio da autonomia deve prevalecer desde que todas as informações sejam devidamente repassadas ao paciente. Objetivou-se relatar um caso de redução por acesso intraoral sem osteossíntese em paciente com fratura de arco zigomático. O procedimentimento foi realizado sob anestesia geral, após o paciente ser informado das possíveis sequelas e complicações caso rejeitasse o tratamento proposto. Atraves do acesso intraoral de Keen foi realizada a redução das fraturas sem intercorrencias e o paciente orientado aos devidos cuidados. Após 30 dias de pós cirurgico paciente apresentou-se recuperado, exercendo as atividades sociais e laborais sem sequelas funcionais ou estéticas. Conclui-se que a técnica de redução sem osteossíntese em fratura de arco zigomático por acesso intraoral, quando indicada, é eficiente e de baixa morbidade.</p> Adolpho Marlon Antoniol de Moura, Douglas Rodrigues Marinho, Bruna Marquezini de Matos Copyright (c) 2021 Multidisciplinary Science Journal Thu, 09 Dec 2021 00:00:00 +0000 Neutrophils of diploid and triploid rainbow trouts assessed by flow cytometry <p>Triploid rainbow trouts <em>Oncorhynchus mykiss</em> are reared in Brazil, but there is no data about haematological differences when compared to diploid ones. Due to the lack of information, the goal was to evaluate the neutrophils of adult diploid and triploid rainbow trouts <em>O. mykiss</em> by flow cytometry screening using a monoclonal anti-neutrophil antibody (TTL-5E9). In comparison, the population of neutrophils was proportionally larger in diploid trouts (9.94 ± 4.64% vs. 5.58 ± 1.09, p = 0.0481), but with cells showing smaller size and less complexity than the neutrophils of triploid trouts. As sorted neutrophils were not evaluated on phagocytic activity or apoptosis induction, it was not possible to establish neutrophil activity differences between ploidies.</p> Renata Stecca Iunes, André Luiz Veiga Conrado, José Roberto Kfoury Junior Copyright (c) 2021 Multidisciplinary Science Journal Wed, 01 Dec 2021 00:00:00 +0000