Amity Institute of Biotechnology, Amity University Chhattisgarh, Raipur-493225, India.
Amity Institute of Biotechnology, Amity University Chhattisgarh, Raipur-493225, India.
Amity Institute of Biotechnology, Amity University Uttar Pradesh, Noida-201313, India.
Council of Industrial Innovation and Research, Noida-201301, India.
Sai Biosystems Pvt. Ltd., Nagpur, Maharashtra, 440009, India.
In the field of nanoparticle research, the green synthesis approach is emerging as a promising avenue, particularly for medical applications. Achyranthes aspera, a plant rich in bioactive compounds, has shown significant potential in the reduction of silver and iron nanoparticles. The validation of this synthesis process is achieved through a thorough examination using spectroscopy, scanning electron microscopy, FTIR, and EDAX techniques. The resulting iron nanoparticles exhibit distinctive properties that influence their stability and agglomeration dynamics. In terms of medicinal utility, both silver and iron nanoparticles exhibit promising antibacterial activity, with silver nanoparticles demonstrating superior effectiveness. Additionally, our investigation provides compelling evidence of anticancer efficacy, with iron nanoparticles showing superior activity against the MCF7 cell line, closely followed by silver nanoparticles. However, both types of nanoparticles exhibit limited antioxidant effectiveness, suggesting a need for further research into alternative antioxidant applications. The synthesis of silver and iron nanoparticles using A. aspera holds significant therapeutic promise, warranting detailed exploration under in vivo conditions to fully realize their medicinal potential. The comprehensive result underscores the importance of leveraging natural resources for advancing nanomedicine.
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