Editorial: The harmfulness of excessive heat on sperm maturation in mammals


  • Maiko Roberto Tavares Dantas Laboratory on Animal Germplasm Conservation, Laboratory of Biometeorology and Environmental Biophysics, Federal University of the Semi-Arid, Mossoró - RN, Brazil




scrotal thermoregulation, environmental influence, epididymal transit, spermatogenesis, sperm quality


Not applicable.


Amann RP, Hammerstedt RH, Veeramachaneni DN (1993) The epididymis and sperm maturation: a perspective. Reprod Fertil Dev. 5:361-381. DOI: 10.1071/RD9930361

Cooper TG (1995) Role of the epididymis in mediating changes in the male gamete during maturation. Adv Exp Med Biol. 377:87-101.

Cooper TG (2011) The epididymis, cytoplasmic droplets and male fertility. Asian. J. Androl. 13:130-138. DOI: 10.1038/aja.2010.97

Cornwall GA (2009) New insights into epididymal biology and function. Human reproduction update 15:213–227.

Dantas MRT, Souza-Junior JBF, Castelo TS, Lago AEA, Silva AR (2021) Understanding how environmental factors influence reproductive aspects of wild myomorphic and hystricomorphic rodents. Anim. Reprod. 18:e20200213.

Erata GO, Koçak Toker N, Durlanik O, Kadioğlu A, Aktan G, Aykaç Toker G (2008) The role of heat shock protein 70 (Hsp 70) in male infertility: is it a line of defense against sperm DNA fragmentation? Fertil Steril 90:322-327. DOI: 10.1016/j.fertnstert.2007.06.021

Gervasi MG, Visconti PE (2017) Molecular changes and signaling events occurring in spermatozoa during epididymal maturation. Andrology 5:204-218. DOI: 10.1111/andr.12320

Hamerezaee M, Dehghan SF, Golbabaei F, Fathi A, Barzegar L, Heidarnejad N (2018) Assessment of semen quality among workers exposed to heat stress: a cross-sectional study in a steel industry. Saf Health Work 9:232-235. DOI: 10.1016/j.shaw.2017.07.003

Huang SY, Tam MF, Hsu YT, Lin JH, Chen HH, Chuang CK, Chen MY, King YT, Lee WC (2005) Developmental changes of heat-shock proteins in porcine testis by a proteomic analysis. Theriogenology 64:1940-1955. DOI: 10.1016/j.theriogenology.2005.04.024

Ivell R (2007) Lifestyle impact and the biology of the human scrotum. Reprod Biol Endocrinol 5:15. DOI: 10.1186/1477-7827-5-15

James ER, Carrell DT, Aston KI, Jenkins TG, Yeste M, Salas-Huetos A (2020) The Role of the Epididymis and the Contribution of Epididymosomes to Mammalian Reproduction. Int J Mol Sci. 21:5377. DOI: 10.3390/ijms21155377

Lin PH, Huang KH, Tian YF, Lin CH, Chao CM, Tang LY, Hsieh KL, Chang CP (2021) Exertional heat stroke on fertility, erectile function, and testicular morphology in male rats. Sci Rep. 11:3539. DOI: 10.1038/s41598-021-83121-3

Llamas-Luceño N, Hostens M, Mullaart E, Broekhuijse M, Lonergan P, Van Soom A (2020) High temperature-humidity index compromises sperm quality and fertility of Holstein bulls in temperate climates. J Dairy Sci. 103:9502-9514

Robaire B, Hinton BT, Orgebin-Crist MC (2006) The epididymis. In ‘Knobil and Neill’s physiology of reproduction’. Nobil E, Neill JD (Eds), pp. 1071-1148.

Sabés-Alsina M, Lundeheim N, Johannisson A, López-Béjar M, Morrell JM (2019) Relationships between climate and sperm quality in dairy bull semen: A retrospective analysis. J Dairy Sci. 102:5623-5633.

Souza APB, Schorr-Lenz ÂM, Lucca F, Bustamante-Filho IC (2017) The epididymis and its role on sperm quality and male fertility. Animal Reproduction 14:1234-1244. DOI: 10.21451/1984-3143-AR955

Sullivan R, Mieusset R (2016) The human epididymis: its function in sperm maturation. Hum Reprod Update 22:574-87.

Zhu Z, Kawai T, Umehara T, Hoque SAM, Zeng W, Shimada M (2019) Negative effects of ROS generated during linear sperm motility on gene expression and ATP generation in boar sperm mitochondria. Free Radic Biol Med. 141:159-171.

Harmful effects on spermatogenesis and sperm maturation of mammals due to prolonged exposure to heat




How to Cite

Dantas, M. R. T. (2022). Editorial: The harmfulness of excessive heat on sperm maturation in mammals. Multidisciplinary Science Journal, 4, e2022014. https://doi.org/10.31893/multiscience.2022014