Keywords:
biomarker
gene sequencing
micro-rna
dna methylation
bacteria
early detection

  • Abstract

    "Nanopore Technology's Impact on Cancer Biomarker Detection" highlights the revolutionary advancements in cancer biomarker detection driven by nanopore technology. This cutting-edge method has demonstrated unprecedented precision and sensitivity, offering promising avenues for early cancer diagnosis and personalized treatment strategies. By facilitating the passage of nucleic acids, proteins, and other cancer-related molecules through nanoscale pores, nanopore technology enables real-time detection and characterization, even for rare and hard-to-detect biomarkers. Its high-throughput nature allows for the identification of genetic mutations, alterations in micro-RNA levels, DNA methylation patterns, and even the presence of specific bacteria associated with cancer progression. The advantages of nanopore platforms extend beyond their sensitivity. These platforms are also portable, cost-effective, and highly scalable, making them suitable for a wide range of clinical and research applications. This includes point-of-care testing in resource-limited environments where traditional diagnostic methods may not be feasible. The integration of nanopore technology with advanced bioinformatics tools further enhances data interpretation, improving the overall accuracy and reliability of cancer biomarker detection. This combination of speed, affordability, and precision makes nanopore technology a game-changer in cancer research and diagnostics. Nanopore technology's versatility means that its impact spans various aspects of cancer research and clinical practice, from early detection and diagnosis to the development of more targeted, individualized treatment strategies. Ongoing research is continually refining nanopore technology, expanding its capabilities, and enabling deeper insights into cancer biology. As these advancements continue, nanopore technology is poised to significantly improve patient outcomes by facilitating earlier detection, more accurate diagnosis, and more effective, personalized treatments for a variety of cancers.

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Ganjare, R., & Vagga, A. (2025). Nanopore technology’s impact on cancer biomarker detection. Multidisciplinary Reviews, 8(11), e2025293. https://doi.org/10.31893/multirev.2025293
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