Keywords:
Magnesium Sulfate
Pregnancy
Obstetric Complications
Neuroprotection
Tocolytic Agents
Maternal-Fetal Medicine

  • Abstract

    Magnesium sulfate is a versatile therapeutic agent in maternal-fetal medicine, and its use during pregnancy has led to various clinical scenarios. This comprehensive review examines the multifaceted role of magnesium sulfate, addressing its benefits and potential risks. The mineral compound is limited for its efficacy in preventing and managing preeclampsia and eclampsia, providing neuroprotection for preterm infants, delaying preterm labor, and offering potential advantages in maternal and fetal health. However, its administration is complex, encompassing a range of maternal and fetal side effects and long-term implications. The decision to utilize magnesium sulfate during pregnancy necessitates a balanced assessment of its advantages and disadvantages, underscored by patient-centered care and shared decision-making. Future research and practice guidelines include pursuing personalized medicine, optimal dosing and administration, long-term follow-up, global health initiatives, and ethical considerations. The evolving landscape of research and emerging insights will continue to enhance maternal care and contribute to improved health outcomes for pregnant women and their infants.

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Wanjari, M., Late, S., Umate, S., Choudhary, M., Munjewar, P., Lohakare, T., Sharma, R., Singh, S., Gawai, J., Taksande, V., Mendhe, D., & Meghe, A. (2024). Role of magnesium sulfate in pregnancy: A comprehensive review of benefits and risks. Multidisciplinary Reviews, 7(11), 2024094. https://doi.org/10.31893/multirev.2024094
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