Grupo de Investigación Bienestar Psicológico, Facultad de Ciencias de la Salud, Universidad Nacional de Chimborazo, Riobamba, Ecuador.
Facultad de Ciencias de la Salud, Universidad Nacional de Chimborazo, Riobamba, Ecuador.
Facultad de Ciencias de la Educación, Sociales, Filosóficos y Humanísticas, Universidad Estatal de Bolívar, Guaranda, Ecuador.
Facultad de Ciencias de la Educación, Sociales, Filosóficos y Humanísticas, Universidad Estatal de Bolívar, Guaranda, Ecuador.
Introduction: University students face high academic stress, social demands, and unequal institutional resources that jeopardize psychological well-being. Learning-oriented approaches are increasingly promoted as preventive supports. Objective: To synthesize evidence on how instructional strategies relate to mental health outcomes in tertiary students. Methods: We conducted a systematic review following PRISMA 2020, searching PubMed, Scopus, Web of Science, and ERIC for 2019–2024 studies. Inclusion required empirical evaluation of a defined strategy and at least one mental-health–relevant outcome. Screening and eligibility proceeded in two stages (titles/abstracts and full texts) after duplicate removal. We summarized outcomes on stress, anxiety, burnout, self-confidence, persistence, and emotion regulation; findings were integrated narratively because interventions and measures were heterogeneous. Results: From 555 records, 20 studies met criteria. Strategies clustered into multimodal approaches; self-regulation frameworks; resilience and academic buoyancy programs; and technology-mediated interventions, including AI-supported tools. Across studies, interventions commonly reduced academic stress, anxiety, and burnout and improved self-regulation, persistence, and emotion regulation. Multimodal and self-regulation–based approaches were frequently associated with better academic performance and lower psychological distress. Online and hybrid delivery tended to foster autonomy and time management, whereas in-person formats supported collaboration and critical thinking. AI-enabled personalization contributed indirectly by increasing engagement, timely feedback, and adaptive pacing. Conclusion: Integrating evidence-based strategies into institutional programming can yield concurrent benefits for mental well-being and academic success. Implications: Universities should scale structured self-regulatory supports, train staff in resilience-focused pedagogy, and evaluate AI-assisted tools with attention to equity, privacy, and transparency. Future research should employ longitudinal, cross-cultural designs and standardized psychological measures to clarify durability and generalizability of effects.

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