TY - JOUR AU - Tran, Thanh Men AU - Tang, Huyen Co AU - Huynh, Hong Phien AU - Nguyen, Yen D. H. AU - Pham, Tuan L. A. AU - Kamei, Kaeko AU - Tran, Duy-Binh PY - 2022/04/11 Y2 - 2024/03/28 TI - Evaluation of the insecticidal activity of Solanum mammosum (L.) fruit extract against Drosophila melanogaster JF - Journal of Animal Behaviour and Biometeorology JA - J. Anim. Behav. Biometeorol. VL - 10 IS - 2 SE - Research Article DO - 10.31893/jabb.22018 UR - https://malque.pub/ojs/index.php/jabb/article/view/253 SP - 2218 AB - <p><em>Solanum mammosum</em> (L.) is known as a poisonous plant and has been extensively used for anti-cancer, antifungal, antibacterial properties. However, the effectiveness of <em>Solanum mammosum</em> against insects has not been fully reported yet. To assess the ability of<em> Solanum mammosum</em> fruit extract against insects, we used fruit fly (<em>Drosophila melanogaster</em>) as a model. In this study, our results showed that phytochemicals and many secondary metabolites were present in <em>Solanum mammosum</em> fruit extracts such as alkaloids, saponins, tannins, terpenoids, coumarins, cardiac glycosides, steroids-triterpenoids, flavonoids, and phenolic compounds. The total polyphenol and flavonoid content were also determined to be 275±1.89 mg GAE/g extract and 676±5.14 mg QE/g extract, respectively. Besides, <em>Solanum mammosum</em> fruit extract caused lethal to 2<sup>nd</sup> instar, reduced a pupae formation rate of <em>Drosophila</em> larvae. Interestingly, <em>Solanum mammosum</em> extract is more effective in the suppression of pupae eclosion than Ascend as a commercial pesticide. These phenomena might be associated with reduced accumulation of energy, including carbohydrates, lipids, and protein. In addition, the activities of esterases and phosphatases were inhibited in <em>Drosophila</em> by the intake of <em>Solanum mammosum</em>. The study concluded that <em>Solanum mammosum</em> has great potential as an insecticidal agent.</p> ER -